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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2117419Generated: October 31, 2026

1,2,3,4-Tetrahydro-7-nitroisoquinoline → (2-Isopropoxy-5-methanesulfonyl-phenyl)-(7-nitro-3,4-dihydro-1H-isoquinolin-2-yl)-methanone

https://huagongshe.com/reaction/2117419

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-Tetrahydro-7-nitroisoquinolineHCID 6424833—
Reactant2-Isopropoxy-5-methylsulfonylbenzoic acidHCID 21100237—
Product(2-Isopropoxy-5-methanesulfonyl-phenyl)-(7-nitro-3,4-dihydro-1H-isoquinolin-2-yl)-methanoneHCID 57445263—

Reaction Steps

Prepared in analogy to example 1.1 from 7-nitro-1,2,3,4-tetrahydro-isoquinoline (CA [42923-79-5]) and 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07442710B2
Source datasetuspto-grants-2008_10
ORD IDord-6f4749789aec481aa8c9181277906886
Source noteuspto-grants-2008_10