HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-1,2,3,4-tetrahydroisoquinoline → (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-isopropylsulfanyl-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-1,2,3,4-tetrahydroisoquinoline | HCID 11789594 | — |
| Reactant | 2-Isopropylsulfanyl-5-methanesulfonyl-benzoic acid | HCID 21100252 | — |
| Product | (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-isopropylsulfanyl-5-methanesulfonyl-phenyl)-methanone | HCID 57445252 | — |
Reaction Steps
Prepared in analogy to example 1.1 from 6-chloro-1,2,3,4-tetrahydro-isoquinoline (CA [33537-99-4]) and 2-isopropylsulfanyl-5-methanesulfonyl-benzoic acid (example 2.7). MS (m/e): 424.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442710B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-f429033cd07342de91e85e4c76b48b0e |
| Source note | uspto-grants-2008_10 |