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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2117449Generated: October 30, 2026

2-Morpholino-5-nitrobenzoic acid → (6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-morpholin-4-yl-5-nitro-phenyl)-methanone

https://huagongshe.com/reaction/2117449

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Morpholino-5-nitrobenzoic acidHCID 2725755—
Reactant6-Chloro-1,2,3,4-tetrahydroisoquinolineHCID 11789594—
Product(6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-(2-morpholin-4-yl-5-nitro-phenyl)-methanoneHCID 57445277—

Reaction Steps

Prepared in analogy to example 1.1 from 6-chloro-1,2,3,4-tetrahydro-isoquinoline (CA [33537-99-4]) and 2-morpholin-4-yl-5-nitro-benzoic acid (example 2.8).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07442710B2
Source datasetuspto-grants-2008_10
ORD IDord-2c44ada27a7b43699fccd3428967c65c
Source noteuspto-grants-2008_10