HCID 69309075, compound → HCID 69310523, compound

Participants

Reaction Steps

A mixture of 10% palladium on charcoal catalyst (100 mg), 4-[2-(3,3-dimethylbut-1-en-1-yl)-1-(propyl)imidazol-5-yl]-2-anilinopyrimidine (Method 114; 230 mg, 0.64 mmol) in ethanol (50 ml) was stirred under an atmosphere of hydrogen for 72 hours. The catalyst was removed by filtration through diatomaceous earth, and the filter pad washed with warm MeOH. The solvent removed by evaporation to give the title compound (200 mg, 86%). M/z 364.

Provenance & Evidence