HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 60668515, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 8-Quinolinecarboxylic acid | HCID 66582 | — |
| Reactant | HOAt | HCID 181649 | — |
| Reactant | Glycinamide hydrochloride | HCID 2723639 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 60668515 | HCID 60668515 | — |
Reaction Steps
To a mixture of quinoline-8-carboxylic acid (3.45 mmol), glycinamide hydrochloride (3.45 mmol), NMM (41.43 mmol) and HOAt (4.14 mmol) in DMF (17 mL) at room temperature was added 1-[3-(dimethylamino)propyl]-3-ethylcarbodimide hydrochloride (4.14 mmol). After stirring at room temperature overnight, the reaction mixture was purified by HPLC to afford the title compound as a white solid. MH+230.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442793B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-fd4d76e6084e421ab4baa4280d3632fc |
| Source note | uspto-grants-2008_10 |