HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418361, compound → HCID 178511305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | 9-[(2R,3R,4S,5R)-5-(azidomethyl)-3,4-dihydroxyoxolan-2-yl]-3H-purin-6-one | HCID 178514594 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178511305 | HCID 178511305 | 91% |
Reaction Steps
The thus-obtained 5′-azido-5′-deoxyinosine was then dissolved in methanol and reduced with hydrogen for 12 hours using palladium-on-carbon Pd/C (10%, 80 mg) as a catalyst, whereby 5′-amino-5′-deoxyinosine was obtained. Yield 91%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442788B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-7881e23a7ddd4bdfa1f4a0a97aada1a0 |
| Source note | uspto-grants-2008_10 |