Cyclopropanecarbonyl chloride → HCID 21925631, compound

HRID 2118031Notes

Reaction equation

HRID 2118031 reaction equation
[CH:1]1([C:4]([Cl:6])=[O:5])[CH2:3][CH2:2]1.[Cl:7][C:8]1[CH:33]=[CH:32][C:11]2[N:12]3[C:16]([CH2:17][NH:18][CH2:19][C:10]=2[CH:9]=1)=[N:15][N:14]=[C:13]3[CH:20]1[CH2:25][CH2:24][N:23]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][N:27]=2)[CH2:22][CH2:21]1>>[ClH:6].[ClH:7].[Cl:7][C:8]1[CH:33]=[CH:32][C:11]2[N:12]3[C:16]([CH2:17][N:18]([C:4]([CH:1]4[CH2:3][CH2:2]4)=[O:5])[CH2:19][C:10]=2[CH:9]=1)=[N:15][N:14]=[C:13]3[CH:20]1[CH2:21][CH2:22][N:23]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][N:27]=2)[CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 113264888-Chloro-1-(3,4,5,6-tetrahydro-2h-[1,2']bipyridinyl-4-yl)-5,6-dihydro4h-2,3,5,10b-tetraaza-benzo[e]azulene

Product 1

HCID 21925631HCID 21925631, compoundYield 50%

Procedure

The title compound was prepared from Cyclopropanecarbonyl chloride and the amine of example 4, in 50% yield, using the procedure described in example 8.

Sources & evidence

ORD record
ord-cb73c29f3d11420ba0fb2b4e27657b3c
Source dataset
uspto-grants-2008_10
Patent number
US07442795B2

Reaction notes

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