HRID2118121

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14797

Potassium hydroxide

HKO

结构：CCOC(=O)c1c(-c2ccccc2)c2cc([N+](=O)[O-])ccc2n1C

HCID69231753

Ethyl 1-methyl-5-nitro-3-phenyl-1H-indole-2-carboxylate

C18H16N2O4

PRODUCTS

生成物

结构：Cn1c(C(=O)O)c(-c2ccccc2)c2cc([N+](=O)[O-])ccc21

HCID21543518

未命名化合物

PROCEDURE

实验过程

1-Methyl-5-nitro-3-phenyl-1H-indole-2-carboxylic acid was prepared from ethyl 1-methyl-5-nitro-3-phenyl-1H-indole-2-carboxylate by KOH hydrolysis as a yellowish solid: 1H NMR (DMSO-d6) δ 4.08 (s, 3H, 7.48-7.55 (m, 5H, 7.86 (d, J=9.2 Hz, 1H), 8.21 (dd, J=9.2, 2.3 Hz, 1H, 8.30 (d, J=2.3 Hz, 1H; MS (ESI) m/z 295 [M-H]−; HRMS calcd for C16H13N2O4: 297.0873; found (ESI+): 297.0867; Anal. calcd for C16H12N2O4.0.15H2O: C, 63.32; H, 4.25; N, 9.23. Found: C, 63.34; H, 3.87; N, 9.12.