HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178500456, compound → HCID 178500457, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178500456 | HCID 178500456 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178500457 | HCID 178500457 | 96% |
Reaction Steps
1.45 g (3.5 mmol) of trans-3-(4-{[methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-methyl}-cyclohexyl)-acrylic acid methyl ester in 25 mL of EtOAc were hydrogenated at normal pressure with 5% Pd/C as the catalyst to give 1.4 g (96%) of trans-3-(4-{[methyl-(4-trifluoromethyl-benzenesulfonyl)-amino]-methyl}-cyclohexyl)-propionic acid methyl ester as white solid, MS: 422 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07442791B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-c6ec9c3f882f433594bba06df7c2f72e |
| Source note | uspto-grants-2008_10 |