Water → HCID 69119810, compound

HRID 2118333Notes

Reaction equation

HRID 2118333 reaction equation
[CH:1]1([S:7][C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([Br:14])[CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.ClC1C=CC=C(C(OO)=[O:23])C=1.[OH2:26]>C(Cl)Cl>[CH:1]1([S:7]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([Br:14])[CH:9]=2)(=[O:23])=[O:26])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 962WaterHCID 70297m-Chloroperbenzoic acidHCID 69119835HCID 69119835, compound

Product 1

HCID 69119810HCID 69119810, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A stirred solution of 3-bromophenyl cyclohexyl sulfide (3.89 g) in DCM (200 ml) under nitrogen was treated with meta-chloroperbenzoic acid (57% pure, 8.69 g), and stirred at room temperature for 1.5 h. The reaction mixture was poured into water and washed with aqueous sodium sulphite until no peracid remained. The organic phase was washed with brine and dried (MgSO4). Filtration and removal of the solvent under reduced pressure gave the title compound (3.63 g). LCMS RT=3.33 min.

Workup

  1. washwashed with aqueous sodium sulphite until no peracid
  2. washThe organic phase was washed with brine
  3. dry with materialdried (MgSO4)
  4. filtrationFiltration and removal of the solvent under reduced pressure

Sources & evidence

ORD record
ord-e4f981f7ec8d403888a2f6fa4cb20f81
Source dataset
uspto-grants-2008_10
Patent number
US07442839B2

Reaction notes

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