HCID 13923772, compound → HCID 20140561, compound

HRID 2118419Notes

Reaction equation

HRID 2118419 reaction equation
[CH3:1][C:2]([NH:5][S:6]([C:9]1[C:18]2[CH:17]([OH:19])[CH2:16][CH2:15][CH2:14][C:13]=2[CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7])([CH3:4])[CH3:3].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl.CCOCC>[CH3:4][C:2]([NH:5][S:6]([C:9]1[C:18]2[C:17](=[O:19])[CH2:16][CH2:15][CH2:14][C:13]=2[CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7])([CH3:1])[CH3:3]

Participants

5

Reactant 2

HCID 13923772HCID 13923772, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 20140561HCID 20140561, compoundYield 97.1%

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent

Procedure

To a solution of 5.49 g (19.4 mmol) of material prepared in Example 11 in 250 mL of methylene chloride was added 8.35 g (39 mmol) of pyridiniumchlorochromate. After 3 hours the reaction mixture was diluted with ether and passed through a plug of fluorosil to give 5.3 g of the title compound as a colorless oil.

Sources & evidence

ORD record
ord-0562072ceb42464d99b6358580a9659c
Source dataset
uspto-grants-1987_07
Patent number
US04678499

Reaction notes

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