Oxygen → HCID 13923986, compound

Participants

Reaction Steps

The title compound was prepared by the method described above for the compounds of Formula I wherein X is oxygen. Thus, 6-(4-chlorobutoxy)-4H-1-benzopyran-4-one, as prepared above in Preparation 3, (3.79 g; 15 mmol) was reacted with 1-phenylpiperazine (2.59 g; 16 mmol) in the usual way, yielding 3.5 g of 6-[4-(4-phenyl-1-piperazinyl)butoxy]-4H-1-benzopyran-4-one as its dihydrochloride salt, mp 193°-195° C. (See Scheme I.)

Provenance & Evidence