1-Chloro-4-(chloromethyl)benzene → HCID 13562959, compound

HRID 2118513Notes

Reaction equation

HRID 2118513 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[CH:9]=[N:8][CH2:7][CH2:6]2.[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20]Cl)=[CH:18][CH:17]=1>C(Cl)CCl>[Cl-:15].[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][N+:8]2[CH2:7][CH2:6][C:5]3[C:10](=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 77231-Chloro-4-(chloromethyl)benzeneHCID 300583,4-Dihydro-6,7-dimethoxyisoquinoline

Product 1

HCID 13562959HCID 13562959, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

The title compound is prepared analogously to Example A from 6,7-dimethoxy-3,4-dihydroisoquinoline and 4-chlorobenzyl chloride in ethylene chloride. Melting point: 182°-184° C. (Decomp.)

Sources & evidence

ORD record
ord-477d1cda383745d4b616e833069bcf43
Source dataset
uspto-grants-1987_07
Patent number
US04678792

Reaction notes

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