Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloral Hydrate | HCID 2707 | — |
| Reactant | HCID 2168799 | HCID 2168799 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 20194016 | HCID 20194016 | — |
Reaction Steps
N-(2-chlorobenzyl)-2-(3,4-dimethoxy-phenyl)-ethylamine (88.4 g, 0.29 mol) is mixed with chloral hydrate (52.5 g, 0.34 mol) and heated (120° C.) for 30 minutes. After cooling, ethyl acetate is added and the mixture is washed with water, dried and evaporated. Yield: 103 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04678792 |
|---|
| Source dataset | uspto-grants-1987_07 |
|---|
| ORD ID | ord-f81acec3ed12420f98405658dec47e3f |
|---|
| Source note | uspto-grants-1987_07 |
|---|
