Methyl iodide → HCID 21246152, compound

HRID 2118534Notes

Reaction equation

HRID 2118534 reaction equation
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([CH:23]([O:27][CH2:28][CH3:29])[O:24][CH2:25][CH3:26])[CH:12]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:2]=[CH2:3].[O-][CH2:31]C.[Na+].CI>CCOCC>[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH:11]([CH:23]([O:24][CH2:25][CH3:26])[O:27][CH2:28][CH3:29])[C:12]([C:18]([O:20][CH2:21][CH3:22])=[O:19])([CH3:31])[C:13]([O:15][CH2:16][CH3:17])=[O:14])[CH:2]=[CH2:3]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 2723922Sodium ethoxideHCID 21246151HCID 21246151, compound

Product 1

HCID 21246152HCID 21246152, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of ethyl 3-(2-allyloxyphenyl)-4,4-diethoxy-2-ethoxycarbonylbutanoate (described in Example 1(i)), in ether is treated with sodium ethoxide and subsequently with methyl iodide to give ethyl 3-(2-allyloxyphenyl)-4,4-diethoxy-2-ethoxycarbonyl-2-methylbutanoate, which is subsequently reacted in a manner similar to that described in Example 1(i) to give 4-(2-allyloxyphenyl)-5-ethoxy-3-methyl-2-oxotetrahydrofuran.

Sources & evidence

ORD record
ord-46d8a8dda47947cfa062ab4299e3bfab
Source dataset
uspto-grants-1987_07
Patent number
US04678786

Reaction notes

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