反应详情

温度

50 °C

30.4 g (0.1 mole) of 2,4,6-trichlorophenoxyethyl bromide were added to a suspension of 48.5 g (0.5 mole) of O-ethylhydroxylamine hydrochloride in 250 ml of ethyldiisopropylamine, and the mixture was stirred for 4 days at 50° C. and then cooled to 15° C. and filtered under suction. The filtrate was evaporated down under reduced pressure, in the final stage at 60° C. and under 0.1 mbar, the residue was dissolved in 300 ml of ether, and the solution was gassed with hydrogen chloride at +3° C. 17 g of O-ethyl-N-(2,4,6-trichlorophenoxy)ethylhydroxylamine hydrochloride of melting point 173°-175° C. were obtained.

1. temperaturecooled to 15° C.
2. filtrationfiltered under suction
3. customThe filtrate was evaporated down under reduced pressure
4. dissolutionin the final stage at 60° C. and under 0.1 mbar, the residue was dissolved in 300 ml of ether
5. customwas gassed with hydrogen chloride at +3° C