4-Chloropyridine → HCID 20028906, compound

HRID 2118608Notes

Reaction equation

HRID 2118608 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[C:8]([C:11]1[CH:18]=[CH:17][C:14]([CH2:15][Br:16])=[CH:13][CH:12]=1)([OH:10])=[O:9]>CC(C)=O>[Br-:16].[Cl:1][C:2]1[CH:7]=[CH:6][N+:5]([CH2:15][C:14]2[CH:17]=[CH:18][C:11]([C:8]([OH:10])=[O:9])=[CH:12][CH:13]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 122884-ChloropyridineHCID 225994-(Bromomethyl)benzoic acid

Product 1

HCID 20028906HCID 20028906, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The starting material was prepared by reaction of 4-chloropyridine with 4-carboxybenzyl bromide in acetone to give 4-chloro-1-(4-carboxybenzyl)pyridinium bromide. n.m.r. in d6DMSO: 5.9(s, 2H); 7.55(d, 2H); 7.9(d, 2H); 8.35(d, 2H); 9.2(d, 2H).

Sources & evidence

ORD record
ord-19db260d74e64790bab6c24ec98e794a
Source dataset
uspto-grants-1987_07
Patent number
US04678781

Reaction notes

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