p-Toluenesulfonic acid → HCID 178427640, compound

HRID 2118673Notes

Reaction equation

HRID 2118673 reaction equation
C(O)(=O)C.[CH:5]1([NH:11][C:12]([NH:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][O:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH:29]=2)=[N:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.[C:38]1([CH3:48])[CH:43]=[CH:42][C:41]([S:44]([OH:47])(=[O:46])=[O:45])=[CH:40][CH:39]=1>O>[C:38]1([CH3:48])[CH:39]=[CH:40][C:41]([S:44]([OH:47])(=[O:45])=[O:46])=[CH:42][CH:43]=1.[CH:14]1([NH:13][C:12]([NH:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][O:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH:29]=2)=[N:11][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 178475355HCID 178475355, compound

Product 1

HCID 178427640HCID 178427640, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

1.0 g of 1,2-dicyclohexyl-3-[6-(2-naphthyloxy)hexyl)guanidine acetate is dissolved in 50 ml water and a solution of 0.39 g of p-toluenesulphonic acid in 10 ml water is then added. The water is then evaporated under vacuum to afford 1,2-dicyclohexyl-3-[6-(2-naphthyloxy)hexyl]guanidine p-toluenesulphonate.

Workup

  1. customThe water is then evaporated under vacuum

Sources & evidence

ORD record
ord-1c7cc19b3e5b46b088349ac6e64fa0c7
Source dataset
uspto-grants-1987_07
Patent number
US04680300

Reaction notes

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