Water → HCID 20192951, compound

HRID 2118746Notes

Reaction equation

HRID 2118746 reaction equation
[C:1]([C:5]1[S:6][C:7]2[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[C:11](Cl)=[CH:10][C:8]=2[N:9]=1)([CH3:4])([CH3:3])[CH3:2].[OH2:18]>N1CCOCC1>[C:1]([C:5]1[S:6][C:7]2[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[C:11]([N:9]3[CH2:8][CH2:7][O:18][CH2:1][CH2:5]3)=[CH:10][C:8]=2[N:9]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 962WaterHCID 197942022-Tert-butyl-5-chloro-6-nitrobenzothiazole

Product 1

HCID 20192951HCID 20192951, compound

Reagents, catalysts & solvents 1

HCID 8083MorpholineSolvent

Procedure

A solution of 170 g of 2-tert-butyl-5-chloro-6-nitrobenzothiazole described in Example 5, in 200 ml of morpholine is refluxed for 6.5 hours, cooled and poured into water. The solid is filtered, washed with water and cold alcohol to give 2-tert-butyl-5-[morpholin-4-yl]-6-nitrobenzothiazole melting at 119°-121°.

Workup

  1. temperatureis refluxed for 6.5 hours
  2. temperaturecooled
  3. filtrationThe solid is filtered
  4. washwashed with water and cold alcohol

Sources & evidence

ORD record
ord-7f49cfba27f64dbfb4625e46239e956b
Source dataset
uspto-grants-1987_07
Patent number
US04680301

Reaction notes

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