HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperidine → [2-(2-Methyl-1-piperidinyl)-5-nitrophenyl]-(4-chlorophenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperidine | HCID 7974 | — |
| Reactant | Calcium Carbonate | HCID 10112 | — |
| Reactant | (2-Chloro-5-nitro-phenyl)-(4-chloro-phenyl)-methanone | HCID 875720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [2-(2-Methyl-1-piperidinyl)-5-nitrophenyl]-(4-chlorophenyl)-methanone | HCID 15072474 | 40.6% |
Reaction Steps
Proceeding as indicated in example 2, from 0.035 mole (10.4 g) of 2,4'-dichloro-5-nitro-benzophenone, 0.07 mole (7 cm3) of 2-methylpiperidine and 0.035 mole (5 g) of calcium carbonate in ethanol, 5.1 g (Yield: 40%) of the expected product are obtained after recrystallization in ethanol. M.P. 142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04680402 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-e0c0303907b14973bc1c7c8f75d278a2 |
| Source note | uspto-grants-1987_07 |