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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2119018Generated: November 3, 2026

Potassium tert-butoxide → HCID 13923639, compound

https://huagongshe.com/reaction/2119018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium tert-butoxideHCID 23665647—
ReactantHCID 57295810HCID 57295810—
SolventTetrahydrofuranHCID 8028—
ProductHCID 13923639HCID 13923639—

Reaction Conditions

Temperature50 °C

Reaction Steps

To a solution of [1-(6-chloro-2-fluorobenzyl)-2-pyrryl](1-methylpiperidin-4-yl)methanol (25.1 g; 0.075 mole) in 230 ml of tetrahydrofuran was added potassium tert-butoxide (9.2 g; 0.082 mole). This was stirred for 0.5 hour at 50° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04681879
Source datasetuspto-grants-1987_07
ORD IDord-bee60824c923474b80df4ceae6dfa1e3
Source noteuspto-grants-1987_07