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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 211905Generated: October 25, 2026

Tetrahydrofuran → 2-anilino-7-chloro-6-fluoro-1-phenyl-5-(trifluoroacetyl)-1,8-naphthyridin-4(1H)-one

https://huagongshe.com/reaction/211905

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
ReactantMethyl trifluoroacetateHCID 9893—
Reactant1,2,2,3-TetramethylpiperidineHCID 18761772—
Reactant2-anilino-7-chloro-6-fluoro-1-phenyl-1,8-naphthyridin-4(1H)-oneHCID 21948186—
ReactantButyllithiumHCID 178418339—
Product2-anilino-7-chloro-6-fluoro-1-phenyl-5-(trifluoroacetyl)-1,8-naphthyridin-4(1H)-oneHCID 21948213—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-4e01e64f763b495fac0db86340b87832
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)