HCID 13921373, compound → 4-Pyridinylacetone

HRID 2119052Notes

Reaction equation

HRID 2119052 reaction equation
C([N:4]1[CH:9]=[CH:8][C:7](=[CH:10][C:11](=[O:13])[CH3:12])[CH:6]=[CH:5]1)(=O)C>C(O)C>[N:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11](=[O:13])[CH3:12])=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 13921373HCID 13921373, compound

Product 1

HCID 805524-PyridinylacetoneYield 98.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 20 g of 1-acetyl-4(acetylmethylidene)-1,4-dihydropyridine was added 30 ml ethanol and the mixture refluxed 4 to 8 hours. Upon removal of solvent, 15 g of 1-(4-pyridinyl)-2-propanone was obtained as a light yellow oil.

Workup

  1. temperaturethe mixture refluxed 4 to 8 hours
  2. customUpon removal of solvent

Sources & evidence

ORD record
ord-d589c2fb3b03486bb70d18bf60ac9913
Source dataset
uspto-grants-1987_07
Patent number
US04681944

Reaction notes

Loading…