HCID 20191014, compound → HCID 20191013, compound

Participants

Reaction Steps

A solution of the above crude ethyl 3-hydroxy-5-(3-nitropyrazol-1-yl)valerate (2.41 g.) in MeOH (250 ml.) was hydrogenated over 5% w/w Pd/carbon (0.3 g.) at atmospheric pressure over 2 hours. Uptake was 650 ml. The catalyst was filtered off and the filtrate was evaporated in vacuo to give ethyl 3-hydroxy-5-(3-aminopyrazol-1-yl)valerate as an oil (1.47 g.).

Provenance & Evidence