HCID 14203475, compound → 83112-44-1

HRID 2119128Notes

Reaction equation

HRID 2119128 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

Participants

4

Reactant 1

HCID 14203475HCID 14203475, compound

Product 1

HCID 1474284483112-44-1

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the presence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen has been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

Workup

  1. customof hydrogen has been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-b0f7db73b5ed48c1a1c0fef1756c3bee
Source dataset
uspto-grants-1987_07
Patent number
US04683232

Reaction notes

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