HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivaloyl chloride → 4-(4-Chlorobenzoyl)phenyl 2,2-dimethylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | 4-Hydroxy-4'-chlorobenzophenone | HCID 123504 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 4-(4-Chlorobenzoyl)phenyl 2,2-dimethylpropanoate | HCID 14010407 | — |
Reaction Steps
2.16 g (0.01 mole) of 4-hydroxy-4'-chlorobenzophenone and 1.2 g (0.015 mole) of pivaloyl chloride in solution were warmed to 50° C. for 3 hrs in 60 mls of dry pyridine with a drying tube attached. The solvent was removed via rotary evaporator and H2O added. The product was filtered and recrystallized from ethanol; 2.3 g (73%) yield; M.P.~113°-114° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04683241 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-b463123c675e41f0973e732260642e87 |
| Source note | uspto-grants-1987_07 |