Pivaloyl chloride → HCID 14010405, compound

HRID 2119177Notes

Reaction equation

HRID 2119177 reaction equation
[OH:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12])=[O:5].[C:17](Cl)(=[O:22])[C:18]([CH3:21])([CH3:20])[CH3:19]>N1C=CC=CC=1>[C:17]([O:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[O:12][C:17](=[O:22])[C:18]([CH3:21])([CH3:20])[CH3:19])=[O:5])(=[O:22])[C:18]([CH3:21])([CH3:20])[CH3:19]

Participants

4

Reactant 2

HCID 62493Pivaloyl chlorideHCID 700382,2'-Dihydroxybenzophenone

Product 1

HCID 14010405HCID 14010405, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2 g (0.01 mole) of 2,2'-dihydroxybenzophenone was dissolved in 30 mls of dry pyridine and 3 g (0.03 mole) of pivaloyl chloride added and contents warmed for 3 hrs. at 50° C. Solvent was removed by rotary evaporator and H2O added and crystals filtered. Recrystallized from ethanol, 3.2 g (83%) yield, M.P.~106°-108° C.

Workup

  1. temperaturecontents warmed for 3 hrs
  2. customat 50° C
  3. customSolvent was removed by rotary evaporator and H2O
  4. additionadded
  5. filtrationcrystals filtered
  6. customRecrystallized from ethanol, 3.2 g (83%)
  7. customyield

Sources & evidence

ORD record
ord-706e9094ad9e4936a5620f3684d5f871
Source dataset
uspto-grants-1987_07
Patent number
US04683241

Reaction notes

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