HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylimidazole → HCID 70387076, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylimidazole | HCID 1390 | — |
| Reactant | 2-Bromo-1-(2,4-dimethylphenyl)ethanone | HCID 2063450 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 70387076 | HCID 70387076 | 51% |
Reaction Steps
A solution of 4.76 g (0.021 mol) of 1-bromo-2-(2,4-dimethylphenyl)-2-oxoethane and 1.76 g (0.021 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room temperature for approximately 21 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was recrystallized from acetonitrile/ethyl acetate to afford 3.32 g of the title product as white crystals. (51% yield) mp=179°-181° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04683312 |
| Source dataset | uspto-grants-1987_07 |
| ORD ID | ord-de65f7ca93cf426faa8057562c722a00 |
| Source note | uspto-grants-1987_07 |