Acetic Acid → HCID 23442326, compound

Participants

Reaction Steps

A suspension of 3-[(9-chloro-1-methyl-1H-pyrazolo[4,3-b]quinolin-7-yl)methyl]benzonitrile (EXAMPLE 28, step 1, 729 mg, 2.19 mmol) in acetic acid (8 ml) and water (8 ml) was refluxed for 5 h. After cooling to room temperature, water (20 ml) was added and the precipitate was collected by filtration. This yellow solid was washed with water, ethanol and hexane to give 594 mg (86%) of the title compound as a yellow solid.

Provenance & Evidence