Methyl iodide → 2-Chlorophenyl methyl sulfide

HRID 2119674Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[CH3:9]I>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH3:9]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 80599o-Chlorothiophenol

Product 1

HCID 27373632-Chlorophenyl methyl sulfideYield 89%

Procedure

2-Chlorothioanisole was prepared in 89% yield from commercially available 2-chlorothiophenol (4.0 g, 27.6 mmol) using methyl iodide (4.66 g, 32.81 mmol) according to the procedure described in preparation 1.

Workup

customdescribed in preparation 1

Sources & evidence

ORD record: ord-d3988462855f4d489543d79de4be0fd4
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06686390B2

Reaction notes

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