反应详情

Under hydrogen atmosphere, a solution of 1.1 g of 5-benzyloxy-4-t-butyl-2-(1-octenyl)benzofuran in 50 ml of acetic acid was stirred with 1.1 g of 10% palladium on carbon for 36 hours. After the palladium on carbon was filtered out, the filtrate was concentrated and the concentrate was purified by silica gel column chromatography (in chloroform) to give 0.6 g of 4-t-butyl-5-hydroxy-2-n-octylbenzofuran as a pale yellow oil (yield 69%).

1. filtrationAfter the palladium on carbon was filtered out
2. concentrationthe filtrate was concentrated
3. customthe concentrate was purified by silica gel column chromatography (in chloroform)