HCID 86586191, compound → HCID 86586192, compound

HRID 2119711Notes

Reaction equation

HRID 2119711 reaction equation
[C:1]([C:5]1[C:19]([OH:20])=[C:18]([CH:21]([CH3:24])[CH:22]=[CH2:23])[C:8]2[CH2:9][C:10]3([O:17][C:7]=2[CH:6]=1)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]3)([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd]>[C:1]([C:5]1[C:19]([OH:20])=[C:18]([CH:21]([CH3:24])[CH2:22][CH3:23])[C:8]2[CH2:9][C:10]3([O:17][C:7]=2[CH:6]=1)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]3)([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 1

HCID 86586191HCID 86586191, compound

Product 1

HCID 86586192HCID 86586192, compoundYield 71%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

0.07 g of 6-t-butyl-5-hydroxy-4-(1-methyl-2-propenyl)-2,3-dihydrobenzofuran-2-spiro-1′-cycloheptane synthesized in Example 12 was dissolved in 10 ml of ethanol and he solution was treated with 0.01 g of 10% palladium on carbon in the same manner as in Example 9 to give 0.05 g of 6-t-butyl-5-hydroxy-4-(1-methylpropyl)-2,3-dihydrobenzofuran-2-spiro-1′-cycloheptane as a pale yellow oil (yield 71%).

Sources & evidence

ORD record
ord-a06a5a1808664712b0f9cf3ba9c9437c
Source dataset
uspto-grants-2004_02
Patent number
US06686389B2

Reaction notes

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