HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cytarabine → Acetamide, N-(1-beta-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cytarabine | HCID 6253 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Product | Acetamide, N-(1-beta-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)- | HCID 83533 | — |
Reaction Steps
introducing an acyl group at the N4 position of 1-β-D-arabinofuranosyl cytosine with an acylating agent, for example using acetic anhydride under conditions suitable for obtaining 1-β-D-arabinofuranosyl-N4-acetyl cytosine,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06686463B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-53fcceddad424ae7b0be80c79fb32a1c |
| Source note | uspto-grants-2004_02 |