5-Chloro-2-methylphenyl isothiocyanate → HCID 9878820, compound

HRID 2119794Notes

Reaction equation

HRID 2119794 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:11])=[C:6]([N:8]=[C:9]=[S:10])[CH:7]=1.[CH3:12][N:13]1[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:11])=[C:6]([NH:8][C:9]([NH:18][C:15]2[CH:16]=[CH:17][N:13]([CH3:12])[N:14]=2)=[S:10])[CH:7]=1

Participants

3

Reactant 2

HCID 295195-Chloro-2-methylphenyl isothiocyanateHCID 1372541-Methyl-3-aminopyrazole

Product 1

HCID 9878820HCID 9878820, compoundYield 95%

Procedure

Prepared using Method A from 4.73 g (27.5 mmol) of 5-chloro-2-methyl-phenyl isothiocyanate and 2.5 g (25.7 mmol) of 1-methyl-3-aminopyrazole to give 6.8 g of title compound as a white solid (95% yield, m.p. 217-218° C.).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ed0cbf841fb348a7b7c654c420e18b88
Source dataset
uspto-grants-2004_02
Patent number
US06686476B2

Reaction notes

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