2-(1H-indol-3-yl)ethanimidamide → 10-Fluoro-5,7-dihydro-2-(1h-indol-3-ylmethyl)-6h-pyrimido[5,4-d][1]benzazepin-6-one

Participants

Role	Name	HCID	Charge
Reactant	2-(1H-indol-3-yl)ethanimidamide	HCID 4046639	—
Reactant	4-Dimethylaminomethylene-7-fluoro-3,4-dihydro-1H-benzo[b]azepine-2,5-dione	HCID 66934610	—
Product	10-Fluoro-5,7-dihydro-2-(1h-indol-3-ylmethyl)-6h-pyrimido[5,4-d][1]benzazepin-6-one	HCID 23440995	87%

Analogous to Scheme 1, from 4-[(dimethylamino)methylene]-7-fluoro-3,4-dihydro-1H-benzazepine-2,5-dione and 2-(1H-indol-3-yl)-acetamidine. Yield: 87%.