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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2119967Generated: October 26, 2026

2-(4-Methoxyphenyl)ethanimidamide hydrochloride → 10-Bromo-5,7-dihydro-2-[(4-methoxyphenyl)methyl]-6h-pyrimido[5,4-d][1]benzazepin-6-one

https://huagongshe.com/reaction/2119967

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methoxyphenyl)ethanimidamide hydrochlorideHCID 12203394—
ReactantHCID 66934668HCID 66934668—
Product10-Bromo-5,7-dihydro-2-[(4-methoxyphenyl)methyl]-6h-pyrimido[5,4-d][1]benzazepin-6-oneHCID 2344097299%

Reaction Steps

Analogous to Scheme 1, from 7-bromo-4-[(dimethylamino)methylene]-3,4-dihydro-1H-benzazepine-2,5-dione and 2-(4-methoxyphenyl)-acetamidine hydrochloride. Yield: 99%. White solid, m/z (ISP) 410/412 (MH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06686352B2
Source datasetuspto-grants-2004_02
ORD IDord-99fa54e1d98f4addb155cd8548a1cac7
Source noteuspto-grants-2004_02