Furfural → HCID 69928159, compound

HRID 2120133Notes

Reaction equation

HRID 2120133 reaction equation
[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([NH2:11])=[N:6][CH:5]=1.C1(C)C=C(C)C=C(C)C=1S(O[NH2:25])(=O)=O.[O:27]1[CH:31]=[CH:30][CH:29]=[C:28]1[CH:32]=O>>[CH3:1][O:2][C:3]([C:4]1[CH:9]=[C:8]([NH2:10])[C:7]2[N:6]([N:25]=[C:32]([C:28]3[O:27][CH:31]=[CH:30][CH:29]=3)[N:11]=2)[CH:5]=1)=[O:12]

Participants

4

Reactant 3

HCID 7362FurfuralHCID 9920476Methyl 5,6-diaminopyridine-3-carboxylateHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

Product 1

HCID 69928159HCID 69928159, compound

Procedure

The title compound, MS m/e (%): 259.1 (M+, 100), was prepared in accordance with the general method of example 1 from 5,6-diamino-nicotinic acid methyl ester, O-mesitylene-sulfonylhydroxylamine, and furan-2-carboxaldehyde. The purification was performed by flash column chromatography on silica eluting with a mixture of ethyl acetate and n-hexane.

Sources & evidence

ORD record
ord-c996bb7c19864711a985411e3982d4e7
Source dataset
uspto-grants-2004_02
Patent number
US06689790B2

Reaction notes

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