HuagongsheHuagongshe Chemistry Print Report · For research reference only
[1-(Pyridin-4-yl)piperidin-4-yl]methanamine → HCID 9873549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [1-(Pyridin-4-yl)piperidin-4-yl]methanamine | HCID 10607746 | — |
| Reactant | HCID 23438734 | HCID 23438734 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 9873549 | HCID 9873549 | 30.9% |
Reaction Steps
A suspension of N-(5-chloropyridin-2-yl)-2,5-dichloropyridine-3-carboxamide (0.807 g, 2.68 mmol) and 1-(4-pyridinyl)piperidine-4-methylamine (510 mg) in ethyl alcohol (5 mL) was heated in a sealed tube for 24 hours. Filtered the solids and purified by RPHPLC. The pure product containing fractions were combined and lyophilized to give 0.1 g of an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689780B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-63a25ed5e5f94c63b9a22d64f0ed29cb |
| Source note | uspto-grants-2004_02 |