HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23438706, compound → HCID 23438738, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23438706 | HCID 23438706 | — |
| Reactant | HCID 23438715 | HCID 23438715 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 23438738 | HCID 23438738 | — |
Reaction Steps
By methods substantially equivalent to those described in example 6-C, N-(5-chloropyridin-2-yl)-4-[(1-isopropylpiperidin-4-ylcarbonyl)amino]pyridine-3-carboxamide hydrochloride (0.219 g, 50%) was prepared from N-(5-chloropyridin-2-yl)-4-[(piperidin-4-ylcarbonyl)amino]pyridine-3-carboxamide trifluoroacetate and acetone. The compound was purified by preparative RPHPLC (C18), eluting with a linear gradient of 95/5 to 60/40 (0.01% HCl/acetonitrile) over 200 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689780B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-77a13dfb5a5b46bd920f9fbc875e3c47 |
| Source note | uspto-grants-2004_02 |