反应详情

To a suspension of 29.2 g of compound obtained in Step A in 25 ml of 95% ethanol there are added 15 ml of hydrochloric acid and 20 ml of water. The mixture is refluxed for 3 hours and put aside at room temperature overnight The solvents are removed under reduced pressure. The residue is treated with 5% NaOH; the solid is collected and washed with water, dried, and crystallised from ethanol giving the title compound.

1. temperatureThe mixture is refluxed for 3 hours
2. customThe solvents are removed under reduced pressure
3. additionThe residue is treated with 5% NaOH
4. customthe solid is collected
5. washwashed with water
6. customdried
7. customcrystallised from ethanol giving the title compound