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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120209Generated: October 25, 2026

Oxindole → 3-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/2120209

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxindoleHCID 321710—
Reactant5-Isopropyl-4-methoxy-2-methylbenzaldehydeHCID 3276129—
Product3-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-oneHCID 54084498—

Reaction Steps

2-Oxindole was condensed with 5-isopropyl-4-methoxy-2-methylbenzaldehyde using method B to give 0.25 g of 3-(5-Isopropyl-4-methoxy-2-methylbenzylidene)-1,3-dihydroindol-2-one as a yellow-orange solid which was reduced using method E to give 2 g (100%) of 3-(5-isopropyl-4-methoxy-2-methylbenzyl)-1,3-dihydroindol-2-one as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06689806B1
Source datasetuspto-grants-2004_02
ORD IDord-8738a5a55d7b40c1afbae0c7c7f4b36d
Source noteuspto-grants-2004_02