Dimethylformamide diethylacetal → HCID 86759329, compound

Participants

Reaction Conditions

Reaction Steps

A 500 ml round-bottomed flask was loaded with 5.58 g of A lactam 15b (20 mmol), 200 ml of dry DMF and 17.1 ml of dimethylformamide diethyl acetal (100 mmol). The mixture was heated at 80° C. for 3 h. The resulting clear solution was concentrated under reduced pressure (0.4 mbar, 60° C. bath temperature) to afford 6.9 g of crude 15c, which was used without further purification.

Provenance & Evidence