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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120406Generated: October 29, 2026

Lithium Hydroxide → HCID 23439302, compound

https://huagongshe.com/reaction/2120406

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 76502387HCID 76502387—
SolventTetrahydrofuranHCID 8028—
ProductHCID 23439302HCID 23439302100%

Reaction Steps

To a solution of quinoxaline-2-carboxylic acid {1-[4-(3-fluoro-3-methyl-butyl)-5-oxo-tetrahydro-furan-2-yl]-2-phenyl-ethyl}-amide (4 g, 8.90 mmol) in tetrahydrofuran was added lithium hydroxide (1 M in water, 28 mL) and stirred for 2 hours. The reaction was then concentrated, and concentrated from benzene (2×) to give the title compound (4.2 g, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06689886B2
Source datasetuspto-grants-2004_02
ORD IDord-df94906a655a4e4abbf864ae6ca1eee8
Source noteuspto-grants-2004_02