HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 23439302, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 76502387 | HCID 76502387 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23439302 | HCID 23439302 | 100% |
Reaction Steps
To a solution of quinoxaline-2-carboxylic acid {1-[4-(3-fluoro-3-methyl-butyl)-5-oxo-tetrahydro-furan-2-yl]-2-phenyl-ethyl}-amide (4 g, 8.90 mmol) in tetrahydrofuran was added lithium hydroxide (1 M in water, 28 mL) and stirred for 2 hours. The reaction was then concentrated, and concentrated from benzene (2×) to give the title compound (4.2 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689886B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-df94906a655a4e4abbf864ae6ca1eee8 |
| Source note | uspto-grants-2004_02 |