HCID 57241908, compound → HCID 9905506, compound

HRID 2120430Notes

Reaction equation

HRID 2120430 reaction equation
[OH:1][C:2]([CH3:24])([CH3:23])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]=[CH:14][C:15]2[CH:16]=[C:17]([OH:22])[CH:18]=[C:19]([OH:21])[CH:20]=2)=[CH:9][CH:8]=1.[H][H]>O1CCOCC1.[Pd]>[OH:1][C:2]([CH3:24])([CH3:23])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][CH2:14][C:15]2[CH:20]=[C:19]([OH:21])[CH:18]=[C:17]([OH:22])[CH:16]=2)=[CH:11][CH:12]=1

Participants

5

Reactant 2

HCID 57241908HCID 57241908, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 9905506HCID 9905506, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

414 mg (1.27 mmol) of 5-{2-[4-(5-hydroxy-5-methylhexyl)phenyl]vinyl}benzene-1,3-diol in 40 ml of dioxane and 42 mg of 10% palladium/carbon are placed in a reactor. A hydrogen pressure of 7 bar is exerted for 4 hours at room temperature. The reaction medium is filtered on celite and the filtrate is evaporated. The product is crystallized from an ethyl acetate/hexane mixture.

Workup

  1. filtrationThe reaction medium is filtered on celite
  2. customthe filtrate is evaporated
  3. customThe product is crystallized from an ethyl acetate/hexane mixture

Sources & evidence

ORD record
ord-ddd0acb08c374a04a6c2c5a222073fe2
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

Loading…