Tetrabutylammonium Fluoride → HCID 69685542, compound

HRID 2120439Notes

Reaction equation

HRID 2120439 reaction equation
[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:30]=[CH:31][C:32]=1[CH2:33][O:34]C(C)(C)C(C)(C)C)[CH2:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]([CH3:29])[CH2:22][CH2:23][CH2:24][C:25]([CH3:28])([OH:27])[CH3:26])[CH:18]=[CH:19][CH:20]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:30]=[CH:31][C:32]=1[CH2:33][OH:34])[CH2:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]([CH3:29])[CH2:22][CH2:23][CH2:24][C:25]([CH3:26])([OH:27])[CH3:28])[CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 23439892HCID 23439892, compound

Product 1

HCID 69685542HCID 69685542, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 3(i), by reacting 50 mg (0.08 mmol) of 6-{3-[3-(tert-butyldimethylsilanyloxymethyl)-4-(1,1,2,2-tetramethylpropoxymethyl)benzyloxy]phenyl}-2-methylheptan-2-ol with 0.17 ml of tetrabutylammonium fluoride 1M/THF, a colourless oil (m=29 mg; Y=94%) is obtained.

Workup

  1. customa colourless oil (m=29 mg; Y=94%) is obtained

Sources & evidence

ORD record
ord-abb9b8cfa45d41188432329421aede5e
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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