Sulfuric Acid → HCID 57097596, compound

Participants

Reaction Conditions

Reaction Steps

0.09 ml of concentrated sulphuric acid are added to 44 mg (0.1 mmol) of [2-hydroxymethyl-5-(2-{3-[5-methyl-5-(tetrahydropyran-2-yloxy)hexyl]-phenyl}vinyl)phenyl]methanol in 1 ml of THF and 1 ml of water. The solution is heated at 40° C. for 48 hours. Water is added and the mixture is extracted with ether. The organic phase is dried over magnesium sulphate and concentrated. The product is triturated in an ether-hexane mixture and is then filtered and dried.

Provenance & Evidence