HCID 69928296, compound → HCID 57030715, compound

HRID 2120441Notes

Reaction equation

HRID 2120441 reaction equation
[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:25]=[CH:26][C:27]2[CH:32]=[CH:31][C:30]([CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]([CH3:47])([CH3:46])[O:39]C3CCCCO3)=[CH:29][CH:28]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][O:17][Si](C(C)(C)C)(C)C)(C(C)(C)C)(C)C>S(=O)(=O)(O)O.C1COCC1.O>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:25]=[CH:26][C:27]2[CH:28]=[CH:29][C:30]([CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]([CH3:47])([OH:39])[CH3:46])=[CH:31][CH:32]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][OH:17]

Participants

5

Reactant 1

HCID 69928296HCID 69928296, compound

Product 1

HCID 57030715HCID 57030715, compound

Reagents, catalysts & solvents 3

HCID 1118Sulfuric AcidCatalystHCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 25(d), by reacting 5 drops of concentrated sulphuric acid with 335 mg (0.49 mmol) of 2-[6-(4-{2-[3,4-bis(tert-butyldimethylsilanyloxymethyl)phenyl]vinyl}phenyl)-1,1-dimethylhexyloxy]tetrahydropyran in 5 ml of THF and 5 ml of water, white crystals (m=94 mg; Y=52%) are obtained. m.p. 112-4° C.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-e46ad915805c4d1c84d8cfff43e6bd80
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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