Sulfuric Acid → HCID 57119515, compound

HRID 2120446Notes

Reaction equation

HRID 2120446 reaction equation
S(=O)(=O)(O)O.[Si]([O:13][C:14]1[CH:15]=[C:16]([CH:28]=[CH:29][C:30]2[CH:31]=[C:32]([CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][C:41]([CH3:50])([CH3:49])[O:42]C3CCCCO3)[CH:33]=[CH:34][CH:35]=2)[CH:17]=[CH:18][C:19]=1[O:20][Si](C(C)(C)C)(C)C)(C(C)(C)C)(C)C>C1COCC1.O>[OH:42][C:41]([CH3:50])([CH3:49])[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36][C:32]1[CH:31]=[C:30]([CH:29]=[CH:28][C:16]2[CH:15]=[C:14]([OH:13])[C:19]([OH:20])=[CH:18][CH:17]=2)[CH:35]=[CH:34][CH:33]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 69925635HCID 69925635, compound

Product 1

HCID 57119515HCID 57119515, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 25(d), by reacting 0.118 ml of concentrated sulphuric acid with 1.38 g (2.11 mmol) of 2-[6-(3-{2-[3,4-bis(tert-butyldimethylsilanyloxy)phenyl]vinyl}phenyl)-1,1-dimethylhexyloxy]tetrahydropyran in 20 ml of THF and 10 ml of water, after purification on a silica column (ethyl acetate 45-heptane 55), a solid having a cottony appearance (m=522 mg; Y=77%) is obtained.

Workup

  1. customafter purification on a silica column (ethyl acetate 45-heptane 55)
  2. customis obtained

Sources & evidence

ORD record
ord-1bae654640474a2d829215711baedbb9
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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