Sulfuric Acid → HCID 57219182, compound

HRID 2120447Notes

Reaction equation

HRID 2120447 reaction equation
S(=O)(=O)(O)O.C([Si](C)(C)[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH:18]=[CH:19][C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][C:31]([CH3:40])([O:33]C3CCCCO3)[CH3:32])[CH:21]=2)[CH:13]=1)(C)(C)C>C1COCC1.O>[OH:33][C:31]([CH3:40])([CH3:32])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][C:22]1[CH:21]=[C:20]([CH:19]=[CH:18][C:14]2[CH:13]=[C:12]([OH:11])[CH:17]=[CH:16][CH:15]=2)[CH:25]=[CH:24][CH:23]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 57112907HCID 57112907, compound

Product 1

HCID 57219182HCID 57219182, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 25(d), by reacting 0.133 ml of concentrated sulphuric acid with 1.25 g (2.39 mmol) of tert-butyldimethyl-[3-(2-{3-[6-methyl-6-(tetrahydropyran-2-yloxy)heptyl]phenyl}-vinyl)phenoxy]silane in 20 ml of THF and 10 ml of water, after crystallization from a heptane/ethyl acetate mixture, white crystals (m=697 mg; Y=90%) are obtained. m.p.=96-7° C.

Workup

  1. customafter crystallization from a heptane/ethyl acetate mixture, white crystals (m=697 mg; Y=90%)
  2. customare obtained

Sources & evidence

ORD record
ord-f4304924609a4ef5a45fa2802f35bcc2
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

Loading…