Tetrabutylammonium Fluoride → HCID 57204616, compound

HRID 2120453Notes

Reaction equation

HRID 2120453 reaction equation
[Si]([O:8][C:9]1[CH:10]=[C:11]([CH:23]=[CH:24][C:25]2[CH:26]=[C:27]([CH:31]=[CH:32][CH2:33][CH2:34][CH2:35][CH2:36][C:37]([CH3:40])([OH:39])[CH3:38])[CH:28]=[CH:29][CH:30]=2)[CH:12]=[CH:13][C:14]=1[O:15][Si](C(C)(C)C)(C)C)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[OH:39][C:37]([CH3:40])([CH3:38])[CH2:36][CH2:35][CH2:34][CH2:33][CH:32]=[CH:31][C:27]1[CH:26]=[C:25]([CH:24]=[CH:23][C:11]2[CH:10]=[C:9]([OH:8])[C:14]([OH:15])=[CH:13][CH:12]=2)[CH:30]=[CH:29][CH:28]=1

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 69685891HCID 69685891, compound

Product 1

HCID 57204616HCID 57204616, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In a manner similar to Example 3(i), by reacting 166 mg (0.286 mmol) of 8-(3-{2-[3,4-bis-(tert-butyldimethylsilanyloxy)phenyl]vinyl}phenyl)-2-methyloct-7-en-2-ol with 0.63 ml of tetrabutylammonium fluoride 1M/THF, after purification on a silica column (ethyl acetate 45-heptane 55), white crystals (m=65 mg; Y=64%) are obtained. m.p.=116-8° C.

Workup

  1. customafter purification on a silica column (ethyl acetate 45-heptane 55), white crystals (m=65 mg; Y=64%)
  2. customare obtained

Sources & evidence

ORD record
ord-6f6f82a83aa04d088a0d09918aec1f18
Source dataset
uspto-grants-2004_02
Patent number
US06689922B1

Reaction notes

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